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Subject: 
Re: LEGO DNA Sculpture
Newsgroups: 
lugnet.build
Date: 
Tue, 3 Apr 2001 19:14:01 GMT
Viewed: 
439 times
  
Don't forget, you only need 2 colors for the links -- C to G, and A to T.
That should cut down on the need for expen$ive orange bricks...

But how to model the directionality of the base chains?  Hmmm...

James Wilson, Research Biologist
Platelet Function Studies Research Laboratory
Dallas VA Medical Center
Dallas, TX 75216

In lugnet.build, John J. Ladasky, Jr. writes:
<snip original post>
Very nice, Eric!

As a biologist, I've been toying with the idea of building a DNA molecule
myself.  Here are some details you might like to know (or, maybe not?):

1) You have eight base-pairs per turn of the helix, an obvious and sensible
choice for Lego modeling.  The pitch of real DNA is sightly over ten bases per
turn.

2) The grooves between the bases are equally spaced in your model, and the base
pairs are represented as straight lines going straight through the central
axis.  In real DNA, there's a "major groove" and a "minor groove," and the
bases do not directly oppose each other.  They meet at an angle.  This also
complicates modeling.

--
John J. Ladasky Jr., Ph.D.
Department of Biology
Johns Hopkins University
Baltimore, MD 21218



Message is in Reply To:
  Re: LEGO DNA Sculpture
 
(...) Very nice, Eric! As a biologist, I've been toying with the idea of building a DNA molecule myself. Here are some details you might like to know (or, maybe not?): 1) You have eight base-pairs per turn of the helix, an obvious and sensible (...) (24 years ago, 3-Apr-01, to lugnet.build)

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